Anyone know anything about this? All I could find, during a brief search today was mention of it's use to counteract the effect of opioids. Anyone got any experience with it?
2 comments:
Anonymous
said...
only thing I know about it is its use in combination meds with paracetamol - it improves pain relief and paracetamol is absorbed faster in this combination. Renner, B., G. Clarke, et al. (2007). "Caffeine Accelerates Absorption and Enhances the Analgesic Effect of Acetaminophen." Journal of Clinical Pharmacology 47: 715-726.
Is it ethical for former presidents of a supposedly scientific organisation to promote homepathy?
Does The Welsh Pharmacist bring the profession into disrepute?
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I do not pretend to represent the views of all Pharmacists, Welsh or otherwise. And for the love of Darwin/God/Buddha/Allah/Satan my ramblings here are not meant to be taken entirely seriously. No-one has to read this blog, and I'm not charging anyone £425 a year to do so.
2 comments:
only thing I know about it is its use in combination meds with paracetamol - it improves pain relief and paracetamol is absorbed faster in this combination. Renner, B., G. Clarke, et al. (2007). "Caffeine Accelerates Absorption and Enhances the Analgesic Effect of Acetaminophen." Journal of Clinical Pharmacology 47: 715-726.
Also, consider caffeine as an antagonist of adenosine. Adenosine involved in peripheral nociception and CNS perception of pain etc etc.
Can't remember receptors or whatnot. University was a long time ago!!
Example article: Nature Reviews Drug Discovery 5, 247-264 (March 2006)
The Cornish Pharmacist
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